Sirindhorn Museum is formerly known as Phu Kum Khao Dinosaur Research Center. In 1994, skeletons of the herbivorous Phuwiangosaurus sirindhornae were discovered in the current excavation site by Provost Wijitt Sahasakhun, the abbot of Sakkawan Temple. Since the end of 1994, dinosaur explorer teams from the Department of Mineral Resources started a thorough and systematic excavation which they found that Phu Kum Khao was Thailand's most complete site for herbivorous dinosaurs' skeletons. Different sizes of dinosaur skeletons were discovered, with more than 7 types of herbivorous dinosaurs identified and resulting in 700 bones. Above all, pieces of skull, teeth and jaw along with scattering bones were still in complete conditions that they could almost make up for the whole body structure. All the bones were located in the rock layer sprawling on the 240 meter-Phu Kum Khao mountain's hay stack-like slopes.

In 1995, Her Royal Highness Princess Maha Chakri Sirindhorn then graciously visited the site and established the development project for Phu Kum Khao Dinosaur Museum. To protect the skeletons, the project started the construction of the temporary building covering the excavation site, and the Department of Mineral Resources built the research building in 1996. The facility with 375-square-meter utility space serves as the center for the conservation, study and research and collection of all fossils found in Thailand.

Officially opened in 2007, Phu Kum Khao Study and Research Center and Museum or Sirindhorn Museum is Thailand's first research center and museum on dinosaurs. The name “Sirindhorn Museum” was graciously given by Her Royal Highness Princess Maha Chakri Sirindhorn.

Sirindhorn Museum comprises 2 exhibition buildings: the first of which features 2 exhibition zones of permanent and temporary ones. Beginning from the 2nd floor, the hall of the museum is used as the information area featuring a model of Siamotyrannusisanensis and information on Thailand's geology. The permanent exhibition is meanwhile divided into 5 zones of:

Zone 1 – The Universe and the World

This zone features stories about the Universe, the World, living beings and long-lost creatures like dinosaurs

Zone 2 - When the First Life Was Born

This zone illustrates the story that happened around 3,400 million years ago when the planet earth was boiling and in turmoil after the volcanic eruption and asteroid impacts. It later cooled down thanks to the atmosphere and water which helped pave the way for living things.

Zone 3 - Paleozoic: Dynamic Era of the Evolution of Life

This zone features the story from the Paleozoic Era which could date back to 542 million years ago. The Era itself is classified in different periods, with models of each period's geographical conditions along with primitive creatures.

Zone 4 - Mesozoic Era

This tells the events during the Mesozoic Era which dated back to 251-65 million years ago.

Zone 5 - Dinosaurs' Lifestyle

This part illustrates the story exclusively about dinosaurs such as their features, types, food, hunting, self-protection, nurturing their young and extinction.

Zone 6 - Bringing Life back to Dinosaurs

This zone delivers information about paleontologists who specialize in fossil conservation worldwide as told from the videos.

Zone 7 - Cenozoic: Dynamic Era of Mammals

The exhibition features evolution of mammals which is classified into 7 periods of Paleocene, Eocene, Oligocene, Miocene, Pliocene, Pleistocene and Holocene.

Zone 8 – The Story of Humans

This tells the story of human evolution and civilization via various exhibition items such as the replica of primitive men's skeletons, drawings, photos, plans and videos.